Signature Process

Using our proprietary Signature Processing techniques and following minimally manipulative procedures, our process does not alter the regenerative properties of the placental tissue. Our products maintain the integrity of the original source material and the relevant characteristics relating to its utility for soft tissue supplementation that is required for tissue repair.

  • All products undergo independent sterility testing and are manufactured in a GMP & GTP Facility.
  • Signature Cord and Signature Matrix are (HCT/P) compliant under Section 361 of the Public Health Service Act according to 21 CFR Part 1271.10. They are regulated as a human cell and tissue product – for homologous use only.
  • Prescription use only for sale to licensed health care professionals.

Signature Cord

Product Description: Signature Cord is derived from Wharton’s Jelly tissue and it is intended to be used as a cushioning agent for homologous supplementation.

Measurement: Signature Cord is measured based on tissue weight and contains 75 mg of tissue per mL. Available vial volume sizes:

  • 1.0 mL vial (75 mg)
  • 1.5 mL vial (112.5 mg)

Filtration: Signature Cord tissue products are available in two types of filtration, Standard and Micro.

  • Signature Cord (Standard) can pass through a 21-gauge or larger diameter needle
  • Signature Cord (Micro) can pass through a 25-gauge or larger diameter needle

Delivery: Our tissue is cryopreserved in 10% DMSO for storage below -65 ̊C and thaws in a gloved hand in less than 5 minutes for application.

Signature Matrix

Product Description: Signature Matrix is derived from the amniotic membrane and is intended to be used as a barrier agent for repair as a wound covering.

Measurement: The product contains hexagon shaped 2.5 mm (0.1 inch) pieces of tissue. Signature Matrix is measured based on tissue weight and contains 135 mg of tissue per mL. Available vial volume sizes:

  • 1.0 mL vial (135 mg)
  • 1.5 mL vial (202.5 mg)

Application: Signature Matrix can be applied topically using sterile forceps or pipette and can pass through a 20-gauge or larger diameter needle.

Delivery: Our tissue is cryopreserved in 10% DMSO for storage below -65 ̊C and thaws in a gloved hand in less than 5 minutes for application.